Self-assembly of phenylalanine-based molecules

Basit Öğe Kaydı
dc.contributor.authorGerman, H.W.
dc.contributor.authorUyaver, Şahin
dc.contributor.authorHansmann, Ulrich H. E.
dc.date.accessioned2020-11-21T15:53:47Z
dc.date.available2020-11-21T15:53:47Z
dc.date.issued2015en_US
dc.departmentİstanbul Ticaret Üniversitesien_US
dc.descriptionPubMed ID: 25347763en_US
dc.description.abstractUsing molecular dynamics, we study the self-assembly of phenylalanine with charged end-groups at various temperatures and concentrations. As in the case of diphenylalanine, we observe the formation of nanotubes; however, phenylalanine aggregates in layers of four, not six, molecules. The observed aggregates are consistent with recent experimental measurements of fibrils obtained from mice with phenylketonuria. We investigate the stability and the mechanism by which these tubular structures form and discuss potential toxicity mechanisms. © 2014 American Chemical Society.en_US
dc.description.sponsorshipNational Science Foundation, NSF: CHE-1266256 -- -- --en_US
dc.identifier.doi10.1021/jp5077388en_US
dc.identifier.endpage1615en_US
dc.identifier.issn1089-5639
dc.identifier.issue9en_US
dc.identifier.pmid25347763en_US
dc.identifier.scopus2-s2.0-84924263240en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1609en_US
dc.identifier.urihttps://doi.org/10.1021/jp5077388
dc.identifier.urihttps://hdl.handle.net/11467/3684
dc.identifier.volume119en_US
dc.identifier.wosWOS:000350840800021en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherAmerican Chemical Societyen_US
dc.relation.ispartofJournal of Physical Chemistry Aen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleSelf-assembly of phenylalanine-based moleculesen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

Scopus İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu