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Öğe Aortic arch and intracardiac repair without circulatory arrest in neonates and infants(Baycinar Medical Publishing, 2014) Karacı, Ali Rıza; Şaşmazel, Ahmet; Dedeoğlu, Reyhan; Aydemir, Numan Ali; Harmandar, Buğra; Erdem, Hasan; Cengiz, DicleBackground: In this article, we aimed to report our surgical experiences with selective antegrade cerebral perfusion combined with the aortic arch and intracardiac surgery in neonates and infants. Methods: Medical data of 27 consecutive patients (18 boys, 9 girls; mean age 9.9+1.7 days; range 1 to 26 days) who undergoing aortic arch and intracardiac repair between March 2007 and April 2012 were retrospectively analyzed. The link between perioperative risk factors and 30-day mortality following surgery were investigated. Results: The mean body weight of patients were 3.2±0.9 kg. Major associated cardiac defects were present in 12 and included truncus arteriosus (Vaan Pragh type 4) (n=2), transposition of the great arteries (n=5), double outlet right ventricle with Taussing Bing anomaly (n=2), and aortopulmonary window defect (n=3). Renal insufficiency and dialysis were statistically significantly associated with mortality [Chi square 27 (p=0.000) and 20.66 (p=0.000), respectively]. Conclusion: Aortic arch repair with simultaneous intracardiac surgical repair can be done with selective antegrade cerebral perfusion at a single stage in neonates and infants.Öğe ASSESSING MYOCARDIAL DEFORMATION OF KAWASAKI PATIENTS WITH SPECKLE-TRACKING ECHOCARDIOGRAPHY ON LONG TERM FOLLOW UP(Bmj Publishing Group, 2016) Şahin, Sezgin; Dedeoğlu, Reyhan; Öztunç, Funda; Barut, Kenan; Cengiz, Dicle; Ugan Atik, Sezen; Kasapçopur, Özgür[Abstract Not Available]Öğe Asymmetric dimethylarginine (ADMA) levels are increased in patients with fibromyalgia: Correlation with tumor necrosis factor-? (TNF-?) and 8-iso-prostaglandin F2? (8-iso-PGF2?)(2011) Topal, Gökçe; Dönmez, Arif; Uydeş-Doğan, B.Sönmez; Kucur, Mine; Cengiz, Dicle; Berkoz, Fatma Begüm; Erdoğan, NergisObjective: The aim of the study was to investigate serum levels of asymmetric dimethylarginine (ADMA), tumor necrosis factor-? (TNF-?), interleukin-6 (IL-6) and plasma levels of 8-iso-prostaglandin F2? (8-iso-PGF2?) in patients with fibromyalgia. Design and method: Twenty-seven patients with fibromyalgia and twenty healthy controls were enrolled in this study. ADMA, TNF-?, IL-6 and 8-iso-PGF2? levels were measured by enzyme-linked immunosorbent assay (ELISA). Results: Serum levels of ADMA and TNF-? and plasma levels 8-iso-PGF2? were significantly increased in patients with fibromyalgia compared to controls. However, no significant difference was observed in IL-6 levels between the two groups. ADMA concentrations were positively correlated with TNF-? and 8-iso-PGF2? levels in patients with fibromyalgia. Conclusion: This is the first study reporting that ADMA levels are significantly elevated in patients with fibromyalgia in association with increased 8-iso-PGF2? and TNF-? concentrations. Thereby, ADMA could be suggested as a reliable marker of endothelial dysfunction in patients with fibromyalgia. © 2011 The Canadian Society of Clinical Chemists.Öğe Create brand rating score with conjoint and structural equational model(Avrasya Bilimler Akademisi, 2017) Kamcı, Veysel; Turanlı, Münevver; Cengiz, DicleCompanies need much more developed data analytic technics to making decision to define the prices of their products. For giving an example for these developed data analytic technics; in this study, with comparing the impact of market share which effected from the proportionally 10 % increasing of “Brand rating score" and effected from the price effect of konjoint analysis, made some simulations for Return on Investment.Öğe Detection of early right ventricular dysfunction in young patients with thalassemia major using tissue doppler imaging(Tehran University of Medical Sciences (TUMS), 2016) Bornaun H.; Dedeoğlu, Reyhan; Oztarhan, K.; Dedeoğlu, S.; Erfidan, E.; Gündoğdu, M.; Cengiz, DicleBackground: Myocardial iron overload is the mostcommoncause of mortality in patients with thalassemia major (TM), alsoknown as beta-thalassemia. T2* cardiovascular magnetic resonance imaging (MRI) is the best way of monitoring cardiac iron, and new echocardiographic techniques can be used to assess cardiac function. Objectives: The aim of this study was to assess the systolic and diastolic right ventricular (RV) function of patients with TM using tissue Doppler imaging (TDI) and to determine whether this echocardiographic technique is an adequate diagnostic tool for the screening and detection of subclinical cardiac dysfunction. Patients and Methods: Eighty-four patients with TM were evaluated by conventional echocardiography and pulse-wave TDI. The data of the TM group (Group 1) were compared with that of 85 age-and sex-matched healthy controls (Group 2). Cardiovascular T2* MRI examinations were performed in 49 of the 85 patients. Results: The patients with TM had significantly lower values for weight, height, body mass index, systolic arterial pressure, deceleration time, E’/A’, and ejection time (ET) than the controls. Group 1 also had significantly higher values for peak early diastolic velocity (E) over peak late diastolic velocity (A), peak early diastolic velocity of TDI (E’), peak late diastolic velocity of TDI (A’), E/E’, isovolumetric relaxation time, isovolumetric contraction time, and RV magnetic perfusion imaging (MPI) than Group 2. Conclusions: RV diastolic dysfunction occurs before systolic deterioration in patients with TM and cannot be screened with conventional echocardiographic techniques. In routine practice, TDI measurements, MPI (for global function) and the E/E’ parameter (for diastolic function) can be used to screen and detect early RV dysfunction. © 2016, Growth & Development Research Center.Öğe Do arbitrage opportunities exist in the natural gas market?(İstanbul Ticaret Üniversitesi, 2016) Turanlı, Münevver; Güriş, Burak; Cengiz, Dicle; Özden, Ünal Halit; Bağdatlı Kalkan, SedaThis paper investigates the relationship between natural gas spot and futures prices by using threshold error correction model developed by Hansen and Seo (2002) and threshold granger causality test developed by Li (2006). We found that there is a threshold cointegration relationship between spot and futures prices of natural gas. We also found that there is partially bidirectional causality between spot and futures prices of natural gas. The evidence obtained from this paper also suggests that there is information flow between natural gas spot and future market and there is no profitable arbitrage opportunity exists.Öğe Erratum to: Evaluation of cardiac functions in juvenile systemic lupus erythematosus with two-dimensional speckle tracking echocardiography(Springer London, 2017) Dedeoğlu, Reyhan; Şahin, Sezgin; Koka, Aida; Öztunç, Funda; Cengiz, Dicle; Barut, Kenan; Kasapçopur, ÖzgürThe authors of the above article contacted the Journal on 29th March 2017, informing the Editor-in-Chief that they had discovered ethical approval was not requested from their Institutional Review Board (IRB) prior to performing the study discussed within the article. The authors explained that the omission of IRB approval resulted from miscommunication between the authorship group and a research fellow who left the group prior to the start of the study. Informed consent was received from all patients included in the study. The authors subsequently submitted a retrospective ethics approval request to their IRB, which was approved on 8th May, 2017. Given the non-invasive nature of the study, the Editors decided that the course of action by the authors was satisfactory. In the interests of transparency, the Journal and the authors wish to share the above with the Journal’s readers. © 2017, International League of Associations for Rheumatology (ILAR).Öğe Evaluation of cardiac functions in juvenile systemic lupus erythematosus with two-dimensional speckle tracking echocardiography(Springer London, 2016) Dedeoğlu, Reyhan; Şahin, Sezgin; Koka, Aida; Öztunç, Funda; Cengiz, Dicle; Barut, Kenan; Kasapçopur, ÖzgürThe aim of this study was to investigate subclinical systolic and diastolic dysfunction in juvenile-onset systemic lupus erythematosus (j-SLE) patients with speckle tracking echocardiography (STE) and the effects of disease activity on left ventricular (LV) regional functions. Thirty-five patients with j-SLE and 30 healthy children (control group) were evaluated between January and August 2015. STE was performed on all patients and controls. Medical records, including diagnosis criteria, age at diagnosis, and duration of disease, were evaluated. SLE disease activity was assessed using the SLE Disease Activity Index (SLEDAI). j-SLE patients had lower ejection fraction than did control subjects but still within normal range. LV end-diastolic and end-systolic dimensions were significantly larger in j-SLE patients (32.43 ± 3.2 vs 28.3 ± 3.1 and 21.1 ± 1.9 vs 18.9.0 ± 2.2, respectively; p = 0.001). There was a significant reduction in longitudinal strain of LV segments in the j-SLE patients compared with controls. J-SLE patients were further divided into subgroups. Group 1 comprised patients having SLEDAI scores >8 at the onset of disease but who improved with therapy during follow-up. Group 2 included j-SLE patients with SLEDAI scores >8 at diagnosis and persistently >4 at the end of follow-up. In the LV mid-inferior and mid-inferolateral segments, STE strain measurements of group 2 were significantly lower than those of group 1 (15.9 ± 6.4 vs 20.0 ± 4.4, 17.9 ± 7.2 vs 23.2 ± 3.8; p = 0.075, p = 0.055, respectively). Simple and non-invasive STE would be helpful in predicting cardiovascular prognosis with new therapeutic medications/interventions or in objectively comparing the effects of immunosuppressive drugs in comparison with preceding STE evaluation. © 2016, International League of Associations for Rheumatology (ILAR).Öğe Evaluation of myocardial deformation in patients with Kawasaki disease using speckle-tracking echocardiography during mid-term follow-up (vol 27, pg 1377, 2017)(Cambridge Univ Press, 2017) Dedeoğlu, Reyhan; Barut, Kenan; Öztunç, Funda; Atik, Sezen; Adrovic, Amra; Sahin, Sezgin; Cengiz, Dicle[Abstract Not Available]Öğe Evaluation of pulmonary artery pressure in patients with juvenile systemic lupus erythematosus (jSLE)(Association of Basic Medical Sciences of FBIH, 2018) Adrovic, Amra; Dedeoğlu, Reyhan; Şahin, Sezgin; Barut, Kenan; Koka, Aida; Cengiz, Dicle; Kasapçopur, ÖzgürJuvenile systemic lupus erythematosus (jSLE) is a chronic multisystemic autoimmune disease. Previous studies among adults have shown impaired right ventricular (RV) function in patients with SLE. Also, these patients may develop pulmonary artery hypertension (PAH), which is one of the most threatening complications of SLE. Nevertheless, studies on PAH among jSLE patients are still rare. The aim of this study was to assess the RV function in jSLE patients by Doppler echocardiography (Echo Doppler). We also estimated pulmonary artery systolic pressure (PASP) and mean pulmonary artery pressure (mPAP) in these patients. A total of 38 jSLE patients and 40 sex- and age-matched controls were retrospectively analyzed. All patients underwent combined M-mode, cross-sectional echo, and Doppler Echo examination. The RV function was significantly impaired in jSLE patients compared to controls. PASP and mPAP were normal in 37 out of 38 patients (97.37%), however, the mean values of PASP and mPAP were significantly higher in jSLE patients compared to controls (26.90 mmHg versus 21.71 mmHg and 12.63 mmHg versus 9.89 mmHg, respectively) [p < 0.05]. Only one patient (2.6 %) had elevated mPAP (60 mmHg). The right cardiac catheterization confirmed PAH in this patient. Although PAH was detected only in one patient, there was a marked increase of PAP in our jSLE patients. Overall, PASP and mPAP were significantly higher in jSLE patients compared to healthy controls. Prospective studies with ethnically diverse cohorts could give more insight on the relevance of PAP and PHT in patients with jSLE. © 2018 ABMSFBIH.Öğe Faktör analizi ile ağırlıklandırarak yetkinlik envanterinin değerlendirmesi ve performans değerlendirmeye etkisi(İstanbul Ticaret Üniversitesi, 2012) Cengiz, Dicle; Hısım, ErimFaktör Analizi sosyal bilimlerde oldukça sık kullanılan bir istatistiksel analizdir. Değişken sayısının fazla olması durumunda indirgeme yapma ve değişkenler arasındaki bağımlılık yapısını ortadan kaldırma amacı ile kullanılmaktadır. Bununla birlikte, değişkenlerin ağırlık vererek değerlendirilmesi konusunda da yararlanılabilmektedir. Bu çalışmanın amacı, faktör analizinin bu özelliklerini yetkinlik envanteri değerlendirmesinde kullanarak, bu değerlendirmeyi objektif hale getirilebileceğini göstermektir. Aynı zamanda yetkinlik envanterinin bu değerlendirme sonuçlarını performans tahmininde kullanılabileceğini istatistiksel olarak gösterilmesi amaçlanmaktadır.Öğe THE ICEBERG IN JUVENILE ONSET SYSTEMIC LUPUS ERYTHEMATOSUS: SUBCLINICAL DETERIORATION OF CARDIAC FUNCTIONS ASSESSED WITH TWO-DIMENSIONAL SPECKLE TRACKING ECHOCARDIOGRAPHY AND CONTRIBUTING FACTORS OF SYSTOLIC DYSFUNCTION(Bmj Publishing Group, 2016) Şahin, Sezgin; Dedeoğlu, Reyhan; Adrovic, Amra; Öztunç, Funda; Barut, Kenan; Cengiz, Dicle; Kasapçopur, Özgür[Abstract Not Available]Öğe İnsan kaynakları yönetiminde grup, grup dinamiği kavramları ve grup dinamiğinin ölçülmesi üzerine uygulama örneği(2011) Dereli, Beliz; Cengiz, DicleGünümüzde örgütlerin içinde bulundukları rekabet koşulları, iç ve dış çevrelerindeki hızlı değişimler dikkate alındığında insan unsurunun ve bireysel başarıdan ziyade grup başarısının önemi daha fazla gün yüzüne çıkmaktadır. Bu nedenle örgütlerin grup oluşumlarını desteklemeleri, grup dinamiklerini gözlemlemeleri, bu dinamikleri doğru yöntemlerle ölçümlemeleri, analiz etmeleri ve tüm bunlara bağlı olarak grup yönetiminde etkin olmaları, genel örgüt başarısı üzerinde son derece önemlidir. Grup ve grup dinamikleri gerek örgütsel davranış gerekse insan kaynakları yönetimi ile ilgili literatürde kapsamlı olarak ele alınan temel konulardır. Dolayısıyla makalede grup ve grup dinamikleri hakkında genel bilgilere yer verilmiş ve örgütler tarafından grup dinamiklerinin ölçülmesinde kullanılan bir yöntem olan senaryoya dayalı gözlem yöntemi, 12 yazılım uzmanından oluşan bir gruba uygulanmış ve sonuçları tartışılmıştırÖğe Kategorik Regresyon Analizi ile Öğrencilerin Benlik Algılarını Etkileyen Özelliklerin Belirlenmesi(2008) Cengiz, DicleÖzet: Kategorik yapıda bir değişkenin kategorilerinin nümerik yapıda bir değişkeni nasıl etkilediğinin istatistiksel olarak incelenmesi, hipotez testleri ya da varyans analizi çözümlemeleri ile yapılabilmektedir. Ancak kategorinin bağımlı değişken üzerindeki etkisinin hesaplanabilmesi için regresyon analizinden yararlanılması gerekmektedir. Bu aşamada ise bağımsız değişkenlerin kategorik yapıda bulunduğu Kategorik Regresyon Analizi'nden bahsedilebilmektedir. Kukla değişkenli regresyon modeline benzerlik gösteren Kategorik Regresyon Analizi kategorilerin yeniden nicelendirilmeleri ve bu niceliklere EKK yönteminin uygulanması ile yorıunlanabilmektedir. Bu çalışmada, ilköğretim öğrencilerinin Benlik Algılarını etkileyen etmenlerin ortaya çıkarılabilmesi amacıyla, 2259 öğrenci ve öğretmenleri üzerinde yapılan bir çalışmanın verilerine Kategorik Regresyon Analizi uygulanmış ve sonuçlar yorumlanmıştır.Öğe Mevduat bankalarının rasyolarına kümelenmesi(2010) Cengiz, DicleTürkiyedeki mevduat bankaları çeşitli rasyo değerlerine gore pek çok çalışmada daha once kümelenmeye çalışılmıştır. Bu çalışmada da benzer şekilde bankaların rasyoları kullanılarak kümelenmesi amaçlanırken, bunun yanında bu amaçla kullanılabilecek kümeleme yöntemlerinin de karşılaştırılması ve uygunluklarının değerlendirilmesi yapılmaya çalışılmıştır. Diğer taraftan, rasyo dışındaki kategorik özellik sayılabilecek bazı özelliklerinin de analize katılması sonucu bankaları kümelenmesinde optimal ölçekleme tekniklerinde de yararlanılmaya çalışılmış ve elde edilen tüm sonuçlar birlikte karşılaştırmalı olarak yorumlanmıştır. Sonuç olarak kümeleme analizinde nominal ve ordinal ölçekli değişkenlerin olması durumunda alternatif bir yöntem çalışmada sunulmuştur.Öğe Türkiye' de illerin eğitim düzeylerine göre kümeleme analizi ile incelenmesi(2012) Cengiz, Dicle; Öztürk, FarukÜlkelerin gelişmişlik düzeylerini belirleyen önemli göstergelerden biri de eğitimdir. Türkiye de bu alanda politakalar üretmekte ve gelişmiş ülkelerin standartlarına ulaşmak istemektedir. Bu bağlamda öncelikle okullaşma oranının artırılmasına yönelik politikalar ile her ilin eğitilmiş nüfusunun artırılması ve gelişme düzeyinin yükseltilmesi amaçlanmaktadır.Türkiye'deki illerin eğitim düzeylerini belirleyen birden çok parametre vardır. Bu çalışmada illerin eğitim düzeyleri, okuma-yazma bilmeyen, okuma-yazma bilen fakat bir okul bitirmeyen, ilköğretim mezunu, ortaöğretim mezunu, yükseköğretim mezunu, yüksek lisans mezunu, doktora mezunu ve eğitim düzeyi bilinmeyen oranları yardımı ile tespit edilmeye çalışılacaktır. Bu nedenle illerin benzerliklerinin belirlenmesinde çok değişkenli istatistik analiz yöntemlerinden olan kümeleme analizi kullanılmıştır.Öğe Volatility modelling for Euro in Turkey(EJBSS, 2015) Turanlı, Münevver; Cengiz, Dicle; Parım, CoşkunA series is formed by taking the logarithm of Euro exchange rate return between January 3, 2000 and December 12, 2014 so as to analyze the volatility structure of Euro exchange rate return in Turkey. Initially, the series is observed to be a stationary one, and optimal autoregressive moving average model is estimated. Later, it has been revealed that the residuals of the mean equation implicate ARCH effect. In addition, heteroscedastic variance model with four different conditions / assumptions has been estimated. It has been proven that ARCH effect is eliminated in these models estimated and no autocorrelation exists in error terms, either. As a result, it has been revealed that among these models the optimal conditional heteroskedasticity model is the TGARCHÖğe Yenidoğan ve infantlarda dolaşım aresti uygulamadan aortik arkus ve intrakardiyak tamiri(2014) Karaci, Ali Rıza; Şaşmazel, Ahmet; Dedeoğlu, Reyhan; Aydemir, Numan Ali; Harmandar, Buğra; Erdem, Hasan; Cengiz, DicleAmaç: Bu yazıda yenidoğan ve infantlarda aortik arkus ve intrakardiyak tamir ile birlikte, selektif antegrad serebral perfüzyon ile yapılan cerrahi deneyimimiz bildirildi.Çalışmaplanı:Mart 2007 - Nisan 2012 tarihleri arasında arkus aort ve intrakardiyak tamiri uygulanan 27 ardışık hastanın (18 erkek, 9 kız; ort. yaş 9.9+1.7 gün, dağılım 1-26 gün) tıbbi verileri retrospektif olarak incelendi. Ameliyat sırası risk faktörleri ve ameliyat sonrası 30 günlük mortalite arasındaki ilişki incelendi.Bul gu lar: Hastaların ortalama vücut ağırlığı 3.2±0.9 kg idi. On iki hastada majör kardiyak defekt vardı ve bunlar trunkus arteriozus (Vaan Pragh tip 4) (n=2), büyük arterlerin transpozisyonu (n=5), çift çıkışlı sağ ventrikülde Taussing Bing anomalisi (n=2) ve aortopulmoner pencere defekti (n=3) idi. Böbrek yetmezliği ve diyaliz ile mortalite arasında istatistiksel olarak anlamlı bir ilişki bulundu [Ki kare, sırasıyla 27 (p=0.000) ve 20.66 (p=0.000)].So nuç: Yenidoğanlarda ve infantlarda, intrakardiyak cerrahi tamir ile eş zamanlı arkus aort tamiri, tek aşamalı selektif antegrad serebral perfüzyon ile yapılabilir.
