Biodegradable Polycaprolactone Fibers with Silica Aerogel and Nanosilver Particles Produce a Coagulation Effect

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dc.authorid0000-0002-1312-5027en_US
dc.authorid0000-0001-6933-2917en_US
dc.authorid0000-0002-3650-7810en_US
dc.authorid0000-0001-6926-3480en_US
dc.contributor.authorAyvazoğlu, Büşra Şengel
dc.contributor.authorCeylan, Muhammet
dc.contributor.authorTuran, Aybüke A. Isbir
dc.contributor.authorYılmaz, Elif Burcu
dc.date.accessioned2023-11-07T13:25:44Z
dc.date.available2023-11-07T13:25:44Z
dc.date.issued2023en_US
dc.departmentFakülteler, Mühendislik Fakültesi, Mekatronik Mühendisliği Bölümüen_US
dc.description.abstractPoly-?-caprolactone (PCL) is a biodegradable aliphatic polyester that can be used in the field of biomaterials. Electrospinning is the name given to the process of producing micro and nanoscale fibers using electrostatically charged polymeric solutions under certain conditions. Almost all synthetic and naturally occurring polymers can undergo electrospinning using suitable solvents or mixtures prepared in certain proportions. In this study, silica aerogels were obtained by the sol-gel method. PCL-silica aerogel fibers were synthesized by adding 0.5, 1, 2, and 4% ratios in the PCL solution. Blood contact analysis was performed on the produced fibers with UV-VIS. According to the results obtained, 0.5, 1, 2, and 4% nano-silver were added to the fiber-containing 4% aerogel. Then, SEM-EDS and FTIR analyses were performed on all fibers produced. Antimicrobial tests were performed on fibers containing nano-silver. As a result, high-performance blood coagulation fibers were developed using PCL with aerogel, and an antimicrobial effect was achieved with nano-silver particles. It is thought that the designed surface will be preferred in wound dressing and biomaterial in tissue engineering, as it provides a high amount of cell adhesion with a small amount of blood and contains antimicrobial properties.en_US
dc.identifier.doi10.3390/polym15092022en_US
dc.identifier.issue9en_US
dc.identifier.pmid37177170en_US
dc.identifier.scopus2-s2.0-85159364067en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.urihttps://hdl.handle.net/11467/6925
dc.identifier.urihttps://doi.org/10.3390/polym15092022
dc.identifier.volume15en_US
dc.identifier.wosWOS:000987730300001en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherMDPIen_US
dc.relation.ispartofPolymersen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectaerogel; antimicrobial effect; coagulation effect; electrospinning; nano-silver; fiber; polycaprolactoneen_US
dc.titleBiodegradable Polycaprolactone Fibers with Silica Aerogel and Nanosilver Particles Produce a Coagulation Effecten_US
dc.typeArticleen_US

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