Predictors of Sexual Dysfunction in Women Seeking Treatment for Opioid Use Disorder: A Comparative Cross-Sectional Study from a Tertiary Center

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dc.contributor.authorSaglam, Nazife Gamze Usta
dc.contributor.authorErgelen, Mine
dc.contributor.authorKilic, Muhsin Koray
dc.contributor.authorBestepe, Engin Emrem
dc.contributor.authorBilici, Rabia
dc.date.accessioned2024-02-12T08:30:17Z
dc.date.available2024-02-12T08:30:17Z
dc.date.issued2023en_US
dc.departmentFakülteler, İnsan ve Toplum Bilimleri Fakültesi, Psikoloji Bölümüen_US
dc.description.abstractAim: There is a critical need for scientific evidence on the sexual and reproductive health of women with opioid use disorder (OUD). The main objective of this study was to evaluate sexual dysfunction (SD) and depression in women with OUD and compare them with healthy controls, in addition to exploring possible predictors of SD. Methods: This cross-sectional study was conducted between January and July 2023. Thirty-four women with OUD, according to the DSM-5, and 30 healthy controls were included. The Female Sexual Function Index (FSFI), Patient Health Questionnaire-9 (PHQ-9), and sociodemographic questionnaire were used to evaluate SD, depression, and characteristics related to substance use and sexual/ reproductive history. Logistic regression analysis was performed to determine the predictors of SD in women with OUD. Results: Twenty-nine percent (n=10) of the participants with OUD had SD. The scores of the FSFI desire, arousal, lubrication, orgasm (p=0.001 for all), satisfaction (p=0.001) subscales, and the total score (p<0.001) were lower in women with OUD than in the controls. Daily dosage of buprenorphine/naloxone [Odds ratio (OR)=1,956, p=0.027, 95% confidence interval (CI)=1,079-3,545] and PHQ-9 score (OR=1,403, p=0.012, 95% CI=1,076-1,829) were significantly associated with SD in women with OUD. Conclusion: The high prevalence of SDs highlights the unmet sexual health needs of women with OUD. Screening and addressing depressive symptoms should be one of the first steps when caring for SDs in women with OUD.en_US
dc.identifier.doi10.4274/haseki.galenos.2023.9493en_US
dc.identifier.endpage365en_US
dc.identifier.issue5en_US
dc.identifier.scopus2-s2.0-85178942744en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage358en_US
dc.identifier.urihttps://hdl.handle.net/11467/7138
dc.identifier.urihttps://doi.org/10.4274/haseki.galenos.2023.9493
dc.identifier.volume61en_US
dc.identifier.wosWOS:001147291900002en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherGalenos Publishing Houseen_US
dc.relation.ispartofHASEKI TIP BULTENI-MEDICAL BULLETIN OF HASEKIen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectOpioid use disorder, sexual dysfunction, depression, female, buprenorphine/naloxone drug combinationen_US
dc.titlePredictors of Sexual Dysfunction in Women Seeking Treatment for Opioid Use Disorder: A Comparative Cross-Sectional Study from a Tertiary Centeren_US
dc.typeArticleen_US

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